What is fourth-generation AI ?
Fourth-generation Artificial Intelligence (Gen-IV AI) refers to the ensemble of trustworthy risk-informed and knowledge-based AI algorithms, augmented with multi-physics methods, mathematics models, and risk engineering techniques, that are implemented to solve complex multi-scale problems with real-world integration and control optimization of operational constraints in compliance with regulatory references. It is inherently interdisciplinary, drawing on mathematics, computer science, engineering, and domain expertise. Gen-IV AI plays a key role in the digital transformation of critical sectors such as healthcare, industry, environment, and society.